Perillyl alcohol (POH) is a naturally occurring dietary monoterpene found in essential oils like lavender, peppermint, and sage. It is primarily researched for its anti-cancer, tumor-inhibiting, and antioxidant properties. Applications include experimental cancer therapy, especially gliomas, with promising results via intranasal administration, as well as use in toiletries and as a potential mosquito repellent.

• Chemical Nature: A monoterpene alcohol (C10H16O) related to limonene.
• Source: Extracted from botanical sources including lavender, peppermint, spearmint, cherries, and celery seeds.
• Appearance: Usually found in oil-based formats, often used in topical applications.

• Anticancer Activity: Inhibits tumor cell growth and promotes apoptosis in various cancers without damaging normal cells.
• Mechanism: Acts on signaling pathways, decreases ras protein prenylation, and acts as an intracellular acidifier.
• Neuroprotective & Anti-inflammatory: Helps protect neurons and reduces inflammation, showing potential for Alzheimer's or Parkinson's disease.
• Antimicrobial: Inhibits the growth of bacteria like E. coli and S. aureus.

Investigated as a chemotherapeutic agent, particularly for treating recurrent malignant glioma via intranasal administration. Also used in topical formulations for skin care, cosmetics, and as a mosquito repellent.